Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy

Now in its second edition, this volume provides focused, single-source coverage of the instrumentation, computerization, calibration, and methods development of NIR spectroscopy. It examines novel applications for accurate time- and cost-effective analyses of pharmaceuticals as well as biomedical applications. Fully updated, the book contains entirely new chapters on the theory of diffuse reflection, the calibration and validation of process sensors, the new field of PAT (Process Analytical Technologies) in pharmaceutical applications, nutraceuticals, detection of counterfeit drugs, NIR spectrometry of abdominal aortic aneurysm, and new chemometric methods for biomedical components in blood and control serum.

Emil W. Ciurczak has degrees in Chemistry from Rutgers and Seton Hall Universities and has been in the pharmaceutical industry since 1970, performing method development. In 1983, he introduced NIR spectroscopy for pharmaceutical applications. He has consulted for numerous instrument companies. He has published over four dozen articles in refereed journals, over 150 magazine columns, and presented nearly two hundred technical papers. Since 2005, Emil has been Contributing Editor forPharmaceutical Manufacturing magazine and wrote for Spectroscopy; (1987-2007). He has taught at colleges since 1979 and presented short courses in the US, Europe, South America, and Asia. He a consultant in the field of NIR and holds a dozen patents for NIR-based devices and software. He was a member of the PAT sub-committee (Validation) for the FDA and is a member of the PAT Expert Committee for the USP. He was the 2004 recipient of the EAS Achievements in NIR Award.

Benoit Igne is a principal scientist at GlaxoSmithKline, King of Prussia, Pennsylvania. From 2010 to 2014, he worked as an industrial research coordinator at Duquesne University, Pittsburgh, Pennsylvania. He received his Ph.D. in Agricultural Engineering from Iowa State University, Ames, Iowa in 2009. He specializes in the implementation of Process Analytical Technologies.